منابع مشابه
Neuronal hemoglobin affects dopaminergic cells' response to stress
Hemoglobin (Hb) is the major protein in erythrocytes and carries oxygen (O2) throughout the body. Recently, Hb has been found synthesized in atypical sites, including the brain. Hb is highly expressed in A9 dopaminergic (DA) neurons of the substantia nigra (SN), whose selective degeneration leads to Parkinson's disease (PD). Here we show that Hb confers DA cells' susceptibility to 1-methyl-4-ph...
متن کاملNeuronal Responses to Physiological Stress
Physiological stress can be defined as any external or internal condition that challenges the homeostasis of a cell or an organism. It can be divided into three different aspects: environmental stress, intrinsic developmental stress, and aging. Throughout life all living organisms are challenged by changes in the environment. Fluctuations in oxygen levels, temperature, and redox state for examp...
متن کاملNatural antisense transcripts regulate the neuronal stress response and excitability
Neurons regulate ionic fluxes across their plasma membrane to maintain their excitable properties under varying environmental conditions. However, the mechanisms that regulate ion channels abundance remain poorly understood. Here we show that pickpocket 29 (ppk29), a gene that encodes a Drosophila degenerin/epithelial sodium channel (DEG/ENaC), regulates neuronal excitability via a protein-inde...
متن کاملResponse of Badami-Zarand Pistachio Rootstock to Salinity Stress
Salinity is one of the most important problems that restrict cultivation of crops in arid and semi-arid regions. Pistachio (Pistacia vera L.) is one of the most important trees that grow in these restricts. In this greenhouse study, the effects of salinity on growth of pistachio rootstock Badami evaluated. Seedlings were grown in plastic bags containing perlite. Salinity was imposed, by adding ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1999
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.114.273